Gambaran Prevalensi Silent Hypoxia Pada Pasien Terkonfirmasi COVID-19

Prevalence of Silent Hypoxia in Confirmed COVID-19 Patients

Authors

  • Ni Luh Suryaningsih STIKES Wira Medika Bali
  • Ni Luh Putu Dewi Puspawati STIKES Wira Medika Bali
  • Ni Komang Ayu Resiyanthi STIKES Wira Medika Bali

DOI:

https://doi.org/10.55887/nrpm.v1i2.19

Abstract

Latar Belakang: COVID-19 adalah virus yang menyerang sistem pernapasan. Fenomena yang sering dijumpai pada pasien terkonfirmasi COVID-19 yaitu sangat susah mendeteksi hipoksia karena pasien tidak menggambarkan kesulitan bernafas sehingga disebut dengan “Silent hypoxia”. Cara yang paling mudah untuk mendeteksi silent hypoxia adalah dengan menggunakan pulse oximetry. Tujuan: Penelitian ini bertujuan untuk menganalisis gambaran prevalensi silent hypoxia pada pasien terkonfirmasi COVID-19 di IRNA D RSUP Sanglah Denpasar. Metode: Penelitian ini merupakan penelitian deskriptif dengan pendekatan retrospektif studi dokumentasi terhadap rekam medis pasien yang terkonfimasi positif COVID-19 antara 1 November 2020 - 31 Januari 2021. Teknik sampling menggunakan total sampling. Hasil: Karakteristik responden terbanyak berdasarkan usia meliputi usia 41-60 tahun sebanyak 213 orang (47,4%). Karakteristik responden berdasarkan jenis kelamin terbanyak adalah laki-laki sebesar 261 orang (58,1%). Karakteristik responden berdasarkan komorbid terbanyak adalah tanpa adanya komorbid sebanyak 247 orang (55%), Dari 449 orang responden 237 orang (52,8%) yang mengalami silent hypoxia. Kesimpulan: Sebagian besar pasien COVID 19 yang dirawat  mengalami silent hypoxia. Silent hypoxia ini disebabkan oleh invasi virus COVID-19 yang merusak persarafan pada sistem pernapasan.

Keywords:

Covid-19, Prevalensi, Silent Hypoxia

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References

Busana, M., Gasperetti, A., Giosa, L., Forleo, G. B., Schiavone, M., Mitacchione, G., Bonino, C., Villa, P., Galli, M., Tondo, C., Saguner, A., Steiger, P., Curnis, A., Dellorusso, A., Pugliese, F., Mancone, M., Marini, J. J., & Gattinoni, L. (2021). Prevalence and outcome of silent hypoxemia in COVID-19. Minerva Anestesiologica, 87(3), 325–333. https://doi.org/10.23736/S0375-9393.21.15245-9 DOI: https://doi.org/10.23736/S0375-9393.21.15245-9

Cen, Y., Chen, X., Shen, Y., Zhang, X., Lei, Y., Xu, C., & Jiang, W. (2020). Risk factors for disease progression in patients with mild to moderate coronavirus disease 2019: a multi-centre observational study. Clinical Microbiology and Infection, 26(January), 1242–1247. https://doi.org/doi.org/10.1016/j.cmi.2020.05.041 DOI: https://doi.org/10.1016/j.cmi.2020.05.041

Chan, K. H., Lee, P. W., Chan, C. Y., Lam, K. B. H., & Ho, P. L. (2020). Monitoring respiratory infections in covid-19 epidemics. The BMJ, 369(May), 1–8. https://doi.org/10.1136/bmj.m1628 DOI: https://doi.org/10.1136/bmj.m1628

Dhont, S., Derom, E., Van Braeckel, E., Depuydt, P., & Lambrecht, B. N. (2021). Conceptions of the pathophysiology of happy hypoxemia in COVID-19. Respiratory Research, 22(1), 1–9. https://doi.org/10.1186/s12931-021-01614-1 DOI: https://doi.org/10.1186/s12931-021-01614-1

Escalera-Antezana, J. P., Lizon-Ferrufino, N. F., Maldonado-Alanoca, A., Alarcón-De-la-vega, G., Alvarado-Arnez, L. E., Balderrama-Saavedra, M. A., Katterine Bonilla-Aldana, D., & Rodríguez-Morales, A. J. (2020). Risk factors for mortality in patients with coronavirus disease 2019 (COVID-19) in Bolivia: An analysis of the first 107 confirmed cases. Le Infezioni in Medicina, 28(2), 238–242.

Guan, W., Ni, Z., Hu, Y., Liang, W., Ou, C., He, J., Liu, L., Shan, H., Lei, C., Hui, D. S. C., Du, B., Li, L., Zeng, G., Yuen, K.-Y., Chen, R., Tang, C., Wang, T., Chen, P., Xiang, J., … Zhong, N. (2020). Clinical Characteristics of Coronavirus Disease 2019 in China. New England Journal of Medicine, 382(18), 1708–1720. https://doi.org/10.1056/nejmoa2002032 DOI: https://doi.org/10.1056/NEJMoa2002032

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Krüger, N., Herrler, T., Erichsen, S., Schiergens, T. S., Herrler, G., Wu, N. H., Nitsche, A., Müller, M. A., Drosten, C., & Pöhlmann, S. (2020). SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell, 181(2), 271-280.e8. https://doi.org/10.1016/j.cell.2020.02.052 DOI: https://doi.org/10.1016/j.cell.2020.02.052

Josephine, N. F. U., Jensen, T. O., Hoyer, N., Ryrsø, C. K., Lindegaard, B., & Harboe, Z. B. (2020). Silent hypoxia in patients with SARS CoV-2 infection before hospital discharge. International Journal of Infectious Diseases, 99(January), 100–101. https://doi.org/doi.org/10.1016/j.ijid.2020.07.014 DOI: https://doi.org/10.1016/j.ijid.2020.07.014

Kementerian Kesehatan Republik Indonesia. (2020). Info Infeksi Emerging Kementerian Kesehatan RI. Https:// Infeksiemerging.Kemkes.Go.Id/.

Li, Y. C., Bai, W. Z., & Hashikawa, T. (2020). The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. Journal of Medical Virology, 92(6), 552–555. https://doi.org/10.1002/jmv.25728 DOI: https://doi.org/10.1002/jmv.25728

Manganelli, F., Vargas, M., Iovino, A., Iacovazzo, C., Santoro, L., & Servillo, G. (2020). Brainstem involvement and respiratory failure in COVID-19. Neurological Sciences, 41(7), 1663–1665. https://doi.org/10.1007/s10072-020-04487-2 DOI: https://doi.org/10.1007/s10072-020-04487-2

Shibata, S., Arima, H., Asayama, K., Hoshide, S., Ichihara, A., Ishimitsu, T., Kario, K., Kishi, T., Mogi, M., Nishiyama, A., Ohishi, M., Ohkubo, T., Tamura, K., Tanaka, M., Yamamoto, E., Yamamoto, K., & Itoh, H. (2020). Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19. Hypertension Research, 43(10), 1028–1046. https://doi.org/10.1038/s41440-020-0515-0 DOI: https://doi.org/10.1038/s41440-020-0515-0

Sun, Q., Qiu, H., Huang, M., & Yang, Y. (2020). Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province. Annals of Intensive Care, 10(33), 2–5. https://doi.org/10.1186/s13613-020-00650-2 DOI: https://doi.org/10.1186/s13613-020-00650-2

Tobin, M. J., Laghi, F., & Jubran, A. (2020). Why COVID-19 silent hypoxemia is baffling to physicians. American Journal of Respiratory and Critical Care Medicine, 202(3), 356–360. https://doi.org/10.1164/rccm.202006-2157CP DOI: https://doi.org/10.1164/rccm.202006-2157CP

Wang, D., Yin, Y., Hu, C., Liu, X., Zhang, X., Zhou, S., Jian, M., Xu, H., Prowle, J., Hu, B., Li, Y., & Peng, Z. (2020). Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China. Critical Care, 24(188), 1–9. https://doi.org/10.1186/s13054-020-02895-6 DOI: https://doi.org/10.1186/s13054-020-02895-6

Whittle, J. S., Pavlov, I., Sacchetti, A. D., Atwood, C., & Rosenberg, M. S. (2020). Respiratory support for adult patients with COVID‐19. Journal of the American College of Emergency Physicians Open, 1(2), 95–101. https://doi.org/10.1002/emp2.12071 DOI: https://doi.org/10.1002/emp2.12071

Wilkerson, R. G., Adler, J. D., Shah, N. G., & Brown, R. (2020). Silent hypoxia: A harbinger of clinical deterioration in patients with COVID-19. American Journal of Emergency Medicine, 38(January), 2242–2243. https://doi.org/doi.org/10.1016/j.ajem.2020.05.044 DOI: https://doi.org/10.1016/j.ajem.2020.05.044

Zhou, P., Yang, X. Lou, Wang, X. G., Hu, B., Zhang, L., Zhang, W., Si, H. R., Zhu, Y., Li, B., Huang, C. L., Chen, H. D., Chen, J., Luo, Y., Guo, H., Jiang, R. Di, Liu, M. Q., Chen, Y., Shen, X. R., Wang, X., … Shi, Z. L. (2020). Erratum: Addendum: A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 588(7836), E6. https://doi.org/10.1038/s41586-020-2951-z DOI: https://doi.org/10.1038/s41586-020-2951-z

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Published

28-06-2022

How to Cite

Suryaningsih, N. L., Puspawati, N. L. P. D. ., & Resiyanthi, N. K. A. . (2022). Gambaran Prevalensi Silent Hypoxia Pada Pasien Terkonfirmasi COVID-19: Prevalence of Silent Hypoxia in Confirmed COVID-19 Patients . Journal Nursing Research Publication Media (NURSEPEDIA), 1(2), 62–71. https://doi.org/10.55887/nrpm.v1i2.19